2. Neurological Disease

Neurological Disease

Neurological Disease

Related Products

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A range of neurological disorders, including epilepsy and dystonia, may involve dysfunctional intracortical inhibition, and may respond to treatments that modify it. Parkinson’s is a neurodegenerative disease characterized by increased activity of GABA in basal ganglia and the loss of dopamine in nigrostriatum, associated with rigidity, resting tremor, gait with accelerating steps, and fixed inexpressive face. Neurological deficits, along with neuromuscular involvement, are characteristic of mitochondrial disease, and these symptoms can have a dramatic impact on patient quality of life. Neurological features may be manifold, ranging from neural deafness, ataxia, peripheral neuropathy, migraine, seizures, stroke‐like episodes and dementia and depend on the part of the nervous system affected.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N7699F
    D-Octamannuronic acid 862694-98-2 98%
    D-Octamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Octamannuronic acid can be used for the research of pain and vascular dementia.
    D-Octamannuronic acid
  • HY-N7699G
    D-Nonamannuronic acid 862694-99-3 98%
    D-Nonamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Nonamannuronic acid can be used for the research of pain and vascular dementia.
    D-Nonamannuronic acid
  • HY-N8290R
    Lactupicrin (Standard) 65725-11-3
    Lactupicrin (Standard) is the analytical standard of Lactupicrin. This product is intended for research and analytical applications. Lactupicrin (Lactucopicrin) exhibits analgesic, sedative, antimalarial activities and atheroprotective effect. Lactupicrin inhibits acetylcholinesterase (AChE) with an IC50 of 150.3 μM. Lactupicrin is an orally active characteristic bitter sesquiterpene lactone.
    Lactupicrin (Standard)
  • HY-N8423R
    α-Amyrin (Standard) 638-95-9
    α-Amyrin (Standard) is the analytical standard of α-Amyrin. This product is intended for research and analytical applications. α-Amyrin is a pentacyclic triterpenoid compound with oral activity. α-Amyrin activates the ERK and GSK-3β signaling pathways. α-Amyrin can be used in the study of metabolic syndrome induced by high fructose diet and cognitive dysfunction caused by low cholinergic neurotransmission.
    α-Amyrin (Standard)
  • HY-N8547A
    (Rac)-Sclerone 19638-58-5 98%
    (Rac)-Sclerone is a natural product, that can be isolated from the green husk of Carya illinoinensis. (Rac)-Sclerone shows appreciable inhibition of AChE, with an IC50 of 192.65 ± 10.12 μg/mL.
    (Rac)-Sclerone
  • HY-N8671R
    Withanoside V (Standard) 256520-90-8
    Withanoside V (Standard) is the analytical standard of Withanoside V. This product is intended for research and analytical applications. Withanoside V, a withanolide glycoside, exhibits inhibitory activity for tachyphylaxis to Clonidine in isolated guinea-pig ileum.
    Withanoside V (Standard)
  • HY-N9241R
    3-Hydroxy-7-methoxyflavone (Standard) 7478-60-6
    Isonicotinamide (Standard) is the analytical standard of Isonicotinamide. This product is intended for research and analytical applications. Isonicotinamide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    3-Hydroxy-7-methoxyflavone (Standard)
  • HY-N9414R
    Acetoxyvalerenic acid (Standard) 84638-55-1
    Acetoxyvalerenic acid (Standard) is the analytical standard of Acetoxyvalerenic acid. This product is intended for research and analytical applications. Acetoxyvalerenic acid is a natural compound that could be found in valerian.
    Acetoxyvalerenic acid (Standard)
  • HY-N9502R
    Linalool oxide (Standard) 60047-17-8
    Linalool oxide (Standard) is the analytical standard of Linalool oxide. This product is intended for research and analytical applications. Linalool oxide is a secondary metabolite in elongating wheat plants with antinociceptive and anticonvulsant effects. Linalool oxide shows anxiolytic activity[1][2][3].
    Linalool oxide (Standard)
  • HY-P0009B
    Cetrorelix diacetate 130143-01-0 98%
    Cetrorelix diacetate (SB-075 diacetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM.
    Cetrorelix diacetate
  • HY-P0033A
    Argireline acetate 2484708-86-1 98%
    Argireline acetate (Acetyl hexapeptide-3 acetate) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline acetate significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline acetate has antiwrinkle and anti-aging activity.
    Argireline acetate
  • HY-P0049A
    Argipressin diacetate 75499-44-4 98%
    Argipressin (diacetate) (AVP (diacetate), also known as antidiuretic hormone (ADH)) is a 9 amino acid neuropeptide secreted by the posterior pituitary. Argipressin (diacetate) (AVP (diacetate)) can regulate the biological effects of fluid balance, osmolality and cardiovascular through three separate G-protein coupled receptors (GPCRs), namely Avpr1a (V1a), Avpr1b (V1b) and Avpr2 (V2). Argipressin (diacetate) (AVP (diacetate)) also have potentially important effects on centrally regulated metabolic processes.
    Argipressin diacetate
  • HY-P0084R
    Cyclic somatostatin (Standard) 38916-34-6
    Cyclic somatostatin (Standard) is the analytical standard of Cyclic somatostatin. This product is intended for research and analytical applications. Cyclic somatostatin (SRIF-14) is a growth hormone-release inhibiting factor used in the research of severe, acute hemorrhages of gastroduodenal ulcers. Cyclic somatostatin is a neuropeptide co-stored with acetylcholine in the cardiac parasympathetic innervation, exerts influences directly on contraction of ventricular cardiomyocytes. Cyclic somatostatin inhibits the contractile response of isoprenaline with an IC50 value of 13 nM. Cyclic somatostatin can be used for the research of cardiovascular disease.
    Cyclic somatostatin (Standard)
  • HY-P0128A
    β-Amyloid (25-35), HFIP-treated 131602-53-4 98%
    β-Amyloid (25-35) (Amyloid beta-peptide (25-35)), HFIP-treated is a β-Amyloid (25-35) (HY-P0128) treated with HFIP. β-Amyloid (25-35) (Amyloid beta-peptide (25-35)) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, has shown neurotoxic activities in cultured cells.
    β-Amyloid (25-35), HFIP-treated
  • HY-P0128F
    FITC-β-Amyloid (25-35) 98%
    FITC-β-Amyloid (25-35) is a FITC (HY-66019) labeled β-Amyloid (25-35) (HY-P0128)
    FITC-β-Amyloid (25-35)
  • HY-P0179A
    β-Casomorphin, bovine TFA 98%
    β-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay.
    β-Casomorphin, bovine TFA
  • HY-P0184A
    Camstatin TFA 98%
    Camstatin TFA, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase.
    Camstatin TFA
  • HY-P0194A
    NocII TFA 98%
    NocII TFA is an orphan neuropeptide which stimulates locomotion in mice.
    NocII TFA
  • HY-P0198B
    [D-Arg25]-Neuropeptide Y (human) 98%
    [D-Arg25]-Neuropeptide Y (human) ([D-Arg25] NPY) is a Y1 receptor selective agonist. Neuropeptide Y (human) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.
    [D-Arg25]-Neuropeptide Y (human)
  • HY-P0201F
    Substance P, FAM-labeled 98%
    Substance P, FAM-labeled is a FAM labeled Substance P (HY-P0201).
    Substance P, FAM-labeled
Cat. No. Product Name / Synonyms Application Reactivity